For patients taking the medicine each day: If you miss a dose or forget to use your medicine in the morning, skip the missed dose and take your medicine the next morning. Do not take two tablets on the same day. Return to your regular schedule the next day. For patients taking the medicine monthly: If you miss your dose and your next scheduled dose is more than 7 days away, take it the next morning after you remember.
Return to your regularly scheduled day of the month for taking your next dose. For patients taking the medicine monthly: If you miss your dose and your next scheduled dose is 1 to 7 days away, wait until then to take your medicine and skip the missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. It is important that your doctor check your progress at regular visits to make sure this medicine is working properly and watch for unwanted effects.
This medicine can irritate your esophagus. If you think this medicine has started to damage your esophagus, stop taking this medicine and call your doctor. Some symptoms of damage to the esophagus are heartburn either new or worse than usual , pain when swallowing, pain in the center of your chest, trouble swallowing, or feeling that food gets stuck on the way to your stomach.
This medicine could lower the amount of calcium in your blood. Call your doctor right away if you develop any signs of low calcium levels, such as muscle spasms or twitching, or numbness or tingling in your fingers, toes, or lips. It is important that you tell all of your health care providers that you are taking ibandronate. If you are having dental procedures while taking ibandronate, you may have an increased chance of getting a severe problem with your jaw.
This may be more common if you use ibandronate for a long time. Make sure you tell your doctor about any new medical problems, especially with your teeth or jaws.
Tell your doctor if you have severe bone, joint, or muscle pain while using this medicine. This medicine may increase your risk of developing fractures of the thigh bone. Check with your doctor right away if you have a dull or aching pain in the thighs, groin, or hips. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription over-the-counter [OTC] medicines and herbal or vitamin supplements.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.
You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. Ibandronate pronounced as i ban' droh nate. Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow? What special dietary instructions should I follow?
What should I do if I forget a dose? What side effects can this medication cause? What should I know about storage and disposal of this medication? Brand names. Ibandronate may not work properly and may damage the esophagus tube between the mouth and stomach or cause sores in the mouth if it is not taken according to the following instructions.
Tell your doctor if you do not understand, you do not think you will remember, or you are unable to follow these instructions: You must take ibandronate just after you get out of bed in the morning, before you eat or drink anything.
Never take ibandronate at bedtime or before you wake up and get out of bed for the day. Swallow the tablets with a full glass 6 to 8 ounces [ to mL] of plain water. Never take ibandronate with tea, coffee, juice, milk, mineral water, sparkling water, or any liquid other than plain water. Swallow the tablets whole; do not split, chew, or crush them. Do not suck on the tablets. After you take ibandronate, do not eat, drink, or take any other medications including vitamins or antacids for at least 60 minutes.
Do not lie down for at least 60 minutes after you take ibandronate. If you take calcium and vitamin D supplements, be sure to take them at least 60 minutes after your Boniva tablet. For any questions about taking calcium and vitamin D supplements while using Boniva, talk with your doctor.
However, drinking heavy amounts of alcohol over many years can increase your risk for osteoporosis weak and brittle bones. Menopause also increases your risk for osteoporosis. Boniva can interact with several other medications.
It can also interact with certain supplements as well as certain foods. Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe. Below is a list of medications that can interact with Boniva.
Before taking Boniva, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.
Boniva tablets can interact with certain antacids and other medications used to help relieve heartburn or indigestion. Taking these medications with Boniva can make Boniva less effective. The medications include products that contain calcium , aluminum, magnesium , or iron. You should take antacids or drugs that contain calcium, aluminum, magnesium, or iron at least 1 hour after taking a Boniva tablet.
This can help lessen your risk for the interaction. Taking Boniva tablets with nonsteroidal anti-inflammatory drugs NSAIDs can increase your risk for certain side effects. NSAIDs can cause an upset or irritated stomach. Taking Boniva tablets can also cause an upset stomach.
Before you start using Boniva tablets, be sure to tell your doctor about all medications you take. If you take these drugs, your doctor may recommend a medication other than Boniva. Herbs or supplements that contain calcium or certain vitamins can interact with Boniva. Be sure to check with your doctor or pharmacist before using any of these products while taking Boniva.
You should avoid eating or drinking anything other than plain water at least 1 hour before and 1 hour after taking Boniva tablets. Bone and joint pain may occur with Boniva use. If you have bone or joint pain, your doctor may perform a bone scan.
This test can help your doctor see if you have a fracture or a more serious bone problem, such as bone cancer. During a bone scan, your doctor may inject a dye that helps your bones show up on the scan. As a result, it would be harder to see your bones on the scan.
There have been no studies that looked at the effects of Boniva on bone scans. If you plan to have a bone scan while taking Boniva tablets or receiving Boniva injections, talk with your doctor.
They can advise you on when you should have your Boniva dose. Based on animal studies, Boniva tablets and Boniva injections harmed the fetus when the drugs were given during pregnancy. They can review the risks and benefits of using Boniva and whether a different medication is right for you. Based on animal studies, taking Boniva tablets may lead to fertility problems trouble conceiving a child.
Animal studies of Boniva injections have shown fertility problems for some women and men. Based on animal studies, Boniva tablets and Boniva injections may be able to pass into breast milk. They can advise you on the pros and cons of the drug and review prevention and treatment options other than Boniva. This drug comes with several precautions. Before taking Boniva, talk with your doctor about your health history.
Boniva may not be right for you if you have certain medical conditions or other factors affecting your health. These include:. Using more than the recommended dosage of Boniva can lead to serious side effects. Do not use more Boniva than your doctor recommends. Symptoms of an overdose can vary depending on the form of Boniva being used.
Symptoms of overdose may include:. You can also call the American Association of Poison Control Centers at or use their online tool. But if your symptoms are severe, call or your local emergency number, or go to the nearest emergency room right away. Doing so can increase your risk for having an irritated esophagus.
When you get Boniva tablets from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. This date is typically 1 year from the date they dispensed the medication. The expiration date helps guarantee that the medication is effective during this time. If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it.
How long a medication remains good can depend on many factors, including how and where you store the medication. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. This helps prevent others, including children and pets, from taking the drug by accident. It also helps keep the drug from harming the environment. This article provides several useful tips on medication disposal.
You can also ask your pharmacist for information on how to dispose of your medication. Both Boniva tablets and Boniva injections are approved for the treatment of postmenopausal osteoporosis. Boniva tablets are also approved for the prevention of postmenopausal osteoporosis.
Boniva tablets are taken once monthly on the same day each month. Boniva tablets should be taken with 6 ounces oz to 8 oz of plain water. Water containing supplements, such as mineral water , should be avoided due to the higher levels of calcium. Boniva tablets should be taken while standing or while sitting up to lessen the chance of an irritated esophagus after swallowing the drug.
The tablets should be swallowed whole. Chewing or sucking the tablets can increase the risk of ulcers in the mouth or throat. Boniva should be taken on an empty stomach. At least 1 hour before and 1 hour after a Boniva tablet dose, patients should avoid eating or drinking anything other than plain water or taking vitamins.
The Boniva injection is given by a healthcare professional once every 3 months. Boniva injections should not be mixed with solutions or other intravenous drugs containing calcium. Boniva is included under the drug classification of bisphosphonates. Boniva works by binding to hydroxyapatite a form of calcium found in bone to reduce the activity of osteoclasts. In turn, this slows down bone resorption and bone turnover. Generally, the bone turnover rate is higher in postmenopause.
In this group of people, using Boniva also results in an overall increase in bone mass. The maximum blood concentration of Boniva occurs between 0. The half-life of Boniva is dose-dependent, ranging from 37 to hours for oral Boniva and from 4. Neither Boniva tablets nor the Boniva injection appear to undergo metabolism. Rarely patients have reported severe bone, joint and muscle pain that begins from 1 day to one month after starting any bisphosphonate, including Ibandronate Sodium.
Most patients report relief from these symptoms after stopping the medication. In rare cases some patients have experienced jaw problems when taking bisphosphonates including Ibandronate Sodium. This included delayed healing and infection. Contact your doctor if you have any questions about this or any of your medications. Contact your doctor if you experience any troubling side effects.
All information contained within the Johns Hopkins Arthritis Center website is intended for educational purposes only. Physicians and other health care professionals are encouraged to consult other sources and confirm the information contained within this site.
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